Thymalin | Peptide Reference Material
RESEARCH PEPTIDE

Thymalin | Peptide Reference Material

Synthetic Thymic Nonapeptide — Research Peptide
$79.00
Supplier-designated Thymalin is a synthetic pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn nonapeptide corresponding to thymulin/serum thymic factor (FTS). It is distinct from historical thymus-derived Thymalin preparations. Research use only; not for human or veterinary use.
✓ Scientific Identity Established
⏳ Laboratory Testing In Progress
⏳ Batch Documentation Pending
✓ Research Use Only
✓ U.S. Fulfillment
In Laboratory Testing
Lot Verification Variant-specific documentation
Traceable Lots VBL lot identification
Primary Literature Peer-reviewed sources
Research Use Only Laboratory research materials

Scientific Specifications

Reference characteristics for laboratory research materials.

CAS Number
63958-90-7
Purity
≥98%
Molecular Formula
C33H54N12O15
Molecular Weight
858.85
Appearance
White lyophilized powder
Storage
-20°C
Research Classification
Research Use Only (RUO). Not for human or veterinary use.

SCIENTIFIC OVERVIEW

Scientific background and research classification for this laboratory reference material.

Thymalin is supplied as a synthetic thymic nonapeptide whose governed molecular identity is thymulin (serum thymic factor), pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn. CAS 63958-90-7; molecular formula C33H54N12O15. The N-terminal residue is pyroglutamate (pGlu; also written '<Glu' or 'Pyr'), and the C-terminus is a free acid. It is supplied as a lyophilized peptide reference material for laboratory research use only.

In this catalog, 'Thymalin' is the supplier/material designation for this defined thymic nonapeptide (scientifically 'thymulin'); it is provided as a single synthetic peptide reference standard rather than a thymic tissue extract.

Primary Research Category
Immune Regulation
Material Type
Lyophilized Peptide
Intended Use
Laboratory Research
Research Categories
Immune Regulation Adaptive Immunity Inflammation

Mechanism of Action

Molecular interaction profile describing how this research material engages receptor systems and influences downstream biological signaling pathways.

Thymulin is a zinc-dependent thymic peptide: its biologically active form is the zinc-bound nonapeptide, and zinc binding has been linked to the conformational epitope associated with its lymphocyte-differentiating activity (Dardenne et al., 1985). It is studied for roles in T-lymphocyte differentiation and immunoregulation. No cloned or characterized receptor for thymulin is represented in the governed molecular-target vocabulary, and zinc functions here as a biological cofactor rather than a governed target; the governed molecular-target and pathway fields are therefore left empty by design, and the governed formula represents the apo-peptide.

Primary Organ Systems
  • Immune System
  • Lymphatic System

Research Documentation

Laboratory documentation is presented when available for the selected product specification and current lot.

In Laboratory Testing
Laboratory Documentation In Progress

Laboratory documentation for the current lot is being completed.

Scientific References
Peer-Reviewed Literature

Explore published literature, clinical investigations, and foundational scientific research.

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Laboratory Resources
Technical Guidance

Storage guidance, handling recommendations, analytical methods, and laboratory best practices.

Related Research
Companion Materials

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Research Center

Scientific literature, laboratory resources, and related materials curated to support research involving this research material.

Scientific References
Peer-Reviewed Literature

Explore curated publications from peer-reviewed journals including clinical investigations, mechanistic studies, and foundational scientific literature.

Browse References →
Scientific Dossier
Deeper Technical Treatment

Comprehensive scientific documentation including literature review, mechanism, pharmacology, and study data for this research material.

Laboratory Resources
Technical Guidance

Storage guidance, handling information, analytical standards, research policies, and laboratory support documentation.

Research Library

Curated peer-reviewed literature selected to provide scientific context for this research material.

Mechanistic Study•Proceedings of the National Academy of Sciences of the United States of America• 1985

A zinc-dependent epitope on the molecule of thymulin, a thymic hormone

Foundational report identifying a zinc-dependent epitope on thymulin, establishing the zinc-dependence of the thymic-hormone nonapeptide's biologically relevant conformation.
Velora Research Insight
Foundational zinc-dependence/thymic-hormone characterization — basis for representing zinc as a cofactor and for the molecular-target vocabulary limitation. Dardenne/Bach originating lineage (Necker/Paris).
PubMed →DOI →
Structural Biology•Biological Chemistry Hoppe-Seyler• 1987

Synthesis and biological activity of eight thymulin analogues

Synthesis of thymulin and eight analogues with evaluation of their biological activity, characterizing structure-activity relationships of the synthetic thymic nonapeptide.
Velora Research Insight
Establishes chemically synthesized thymulin and its structure-activity relationships — directly relevant to a synthetic reference material. Same Dardenne/Bach originating lineage (Pléau et al.); investigator concentration disclosed.
PubMed →DOI →
Review Article•Current Aging Science• 2013

Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?

Independent review examining zinc, thymulin, and neuroendocrine-thymus interactions in ageing, synthesizing evidence on thymic-peptide function and immunosenescence.
Velora Research Insight
Fully independent later synthesis (Mocchegiani group, Italy; no Dardenne/Bach overlap) situating thymulin within zinc/ageing/immunosenescence research; carried as evidence-scoped context, not a product efficacy claim.
PubMed →DOI →
Review Article•Critical Reviews in Oncology/Hematology• 1985

Thymic peptide hormones: basic properties and clinical applications in cancer

Independent review of thymic peptide hormones, including thymulin, summarizing their basic properties and the historical scope of clinical investigation.
Velora Research Insight
Independent review (Schulof) placing thymulin among thymic peptide hormones; historical clinical-investigation context is retained at evidence level and is not represented as efficacy of this research material.
PubMed →DOI →