PT-141 is a cyclic melanocortin peptide analogue studied in melanocortin-receptor pharmacology; salt form and molecular mass remain under scientific review. Research use only; not for human or veterinary use.
Reference characteristics for laboratory research materials.
CAS Number
1607799-13-2
Purity
≥98%
Molecular Formula
C50H68N14O10
Molecular Weight
1025.16
Appearance
White lyophilized powder
Storage
-20°C
Research Classification
Research Use Only (RUO). Not for human or veterinary use.
SCIENTIFIC OVERVIEW
Scientific background and research classification for this laboratory reference material.
This catalog material is labeled PT-141 / bremelanotide. Supplied records conflict on base versus acetate form and molecular mass; no disputed exact form, formula, mass, or salt value is adopted here. Research use only.
Primary Research Category
Pigmentation & Receptor Biology
Material Type
Lyophilized Peptide
Intended Use
Laboratory Research
Research Categories
Melanocortin BiologyReceptor PharmacologyReceptor BindingMechanism of Action
Mechanism of Action
Molecular interaction profile describing how this research material engages receptor systems and influences downstream biological signaling pathways.
No product-specific receptor pharmacology is assigned until material form and molecular identity are independently resolved. Literature for a defined bremelanotide form is contextual only.
Molecular Targets
Melanocortin-4 Receptor (MC4R)
Melanocortin-1 Receptor (MC1R)
Primary Organ Systems
Central Nervous System
Research Documentation
Laboratory documentation is presented when available for the selected product specification and current lot.
In Laboratory Testing
Laboratory Documentation In Progress
Identity
Purity
Endotoxin
Fentanyl
Independent laboratory verification for this batch:
Storage guidance, handling recommendations, analytical methods, and laboratory best practices.
Related Research
Companion Materials
Discover complementary research materials frequently studied alongside this compound.
Research Center
Scientific literature, laboratory resources, and related materials curated to support research involving this research material.
Scientific References
Peer-Reviewed Literature
Explore curated publications from peer-reviewed journals including clinical investigations, mechanistic studies, and foundational scientific literature.
Comprehensive scientific documentation including literature review, mechanism, pharmacology, and study data for this research material.
Laboratory Resources
Technical Guidance
Storage guidance, handling information, analytical standards, research policies, and laboratory support documentation.
Research Library
Curated peer-reviewed literature selected to provide scientific context for this research material.
Clinical Trial•Obstetrics & Gynecology•2019
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
Two randomized, double-blind, placebo-controlled phase-3 trials (RECONNECT) evaluating bremelanotide in premenopausal women with hypoactive sexual desire disorder.
Velora Research Insight
Primary clinical research context for bremelanotide. Palatin clinical-development sponsor lineage (shared with VSE-PUB-000069). Cited as scientific context only, not a therapeutic representation of this research material.
The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women
Review of the melanocortin neurobiology and central mechanism of action of bremelanotide, identifying MC4R activation as the principal central mediator.
Velora Research Insight
Melanocortin/MC4R mechanism-of-action anchor. Palatin sponsor lineage (author Spana; Clayton shared with VSE-PUB-000068) — counted as one lineage, not two.
Independent Adis regulatory/development summary of bremelanotide at first approval, consolidating its pharmacology and clinical-development milestones.
Velora Research Insight
Independent secondary synthesis (Adis/Springer editorial), not sponsor-authored. Consolidates identity and development context.
Systematic Review•The Journal of Sex Research•2024
Small Effects, Questionable Outcomes: Bremelanotide for Hypoactive Sexual Desire Disorder
Independent critical appraisal of the bremelanotide clinical-trial evidence base, examining effect sizes and outcome interpretation.
Velora Research Insight
Fully independent, skeptical evidence synthesis included deliberately for balance; represents the clinical literature critically rather than promotionally.