Epitalon | Peptide Reference Material
RESEARCH PEPTIDE

Epitalon | Peptide Reference Material

Synthetic Tetrapeptide (AEDG) — Research Peptide
$29.00
Epitalon (Ala-Glu-Asp-Gly; AEDG) is a synthetic tetrapeptide studied in cell and animal models of pineal-peptide biology and telomerase-related cellular markers. Research use only; not for human or veterinary use.
✓ Scientific Identity Established
⏳ Laboratory Testing In Progress
⏳ Batch Documentation Pending
✓ Research Use Only
✓ U.S. Fulfillment
In Laboratory Testing
Lot Verification Variant-specific documentation
Traceable Lots VBL lot identification
Primary Literature Peer-reviewed sources
Research Use Only Laboratory research materials

Scientific Specifications

Reference characteristics for laboratory research materials.

CAS Number
307297-39-8
Purity
≥98%
Molecular Formula
C14H22N4O9
Molecular Weight
390.35
Appearance
White lyophilized powder
Storage
-20°C
Research Classification
Research Use Only (RUO). Not for human or veterinary use.

SCIENTIFIC OVERVIEW

Scientific background and research classification for this laboratory reference material.

The supplier COA for Epithalon lot P251018-B024 identifies a chemically synthesized Ala-Glu-Asp-Gly tetrapeptide, CAS 307297-39-8, formula C14H22N4O9, and reported molecular weight 390.35. Independent reference identity recognizes the AEDG tetrapeptide as Epitalon/Epithalon. The COA measures acetate and TFA content but does not declare a discrete salt stoichiometry; the supplied material is therefore not described here as a particular salt form. Published cell and animal-model work has investigated pineal-peptide biology and telomerase/telomere-related markers; those findings do not establish rejuvenation, longevity, or human therapeutic effects.

Primary Research Category
Longevity & Cellular Health
Material Type
Lyophilized Peptide
Intended Use
Laboratory Research
Research Categories
Longevity Cellular Senescence

Mechanism of Action

Molecular interaction profile describing how this research material engages receptor systems and influences downstream biological signaling pathways.

In cultured human somatic cells, AEDG has been reported to increase telomerase activity and telomere length. Later in-vitro work reported telomere-length changes associated with telomerase upregulation or alternative lengthening of telomeres in particular cell lines. These are model-dependent cellular observations; they do not establish a general anti-aging mechanism, organismal longevity effect, or human therapeutic mechanism.

Research Documentation

Laboratory documentation is presented when available for the selected product specification and current lot.

In Laboratory Testing
Laboratory Documentation In Progress

Laboratory documentation for the current lot is being completed.

Scientific References
Peer-Reviewed Literature

Explore published literature, clinical investigations, and foundational scientific research.

View References →
Laboratory Resources
Technical Guidance

Storage guidance, handling recommendations, analytical methods, and laboratory best practices.

Related Research
Companion Materials

Discover complementary research materials frequently studied alongside this compound.

Research Center

Scientific literature, laboratory resources, and related materials curated to support research involving this research material.

Scientific References
Peer-Reviewed Literature

Explore curated publications from peer-reviewed journals including clinical investigations, mechanistic studies, and foundational scientific literature.

Browse References →
Scientific Dossier
Deeper Technical Treatment

Comprehensive scientific documentation including literature review, mechanism, pharmacology, and study data for this research material.

Laboratory Resources
Technical Guidance

Storage guidance, handling information, analytical standards, research policies, and laboratory support documentation.

Research Library

Curated peer-reviewed literature selected to provide scientific context for this research material.

Mechanistic Study•Bulletin of Experimental Biology and Medicine• 2003

Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells

Foundational in-vitro report that the AEDG tetrapeptide induces telomerase activity and telomere elongation in cultured human somatic cells.
Velora Research Insight
Origin in-vitro claim for Epitalon's telomerase mechanism. Khavinson-lineage source — labeled as the founding, non-independent report.
PubMed →DOI →
Mechanistic Study•Biogerontology• 2025

Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity

Independent in-vitro study reporting that Epitalon increases telomere length in human cell lines via telomerase upregulation or alternative-lengthening-of-telomeres (ALT) activity.
Velora Research Insight
Independent (non-Khavinson) replication of telomere lengthening in human cell lines — the key evidence-independence anchor. A published correction exists (PMID 41240216); the original stands as corrected.
PubMed →DOI →
Preclinical Study•Life Sciences• 2025

Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development

Independent animal-cell study reporting that Epitalon-activated telomerase enhances bovine oocyte maturation rate and post-thaw embryo development.
Velora Research Insight
Independent (non-Khavinson) replication in a distinct experimental model, extending telomerase-activation observations beyond human cell lines.
PubMed →DOI →
Review Article•International Journal of Molecular Sciences• 2025

Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties

Independent overview synthesizing the physicochemical properties and reported bioactivity of the Epitalon tetrapeptide across the research literature.
Velora Research Insight
Independent (non-Khavinson) synthesis providing balanced context for the compound's research profile.
PubMed →DOI →